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Biomechanical Engineering

You are here: Home / Archives for Biomechanical Engineering

Research Interest

Bone Biomechanics Lab

The Bone Biomechanics Lab — originally called the Berkeley Orthopedic Biomechanics Laboratory — was established by Professor Tony Keaveny in 1993. Together with Professor Grace O’Connell, Professor Keaveny now co-directs the Berkeley BioMechanics Lab in the Department of Mechanical Engineering at the University of California, Berkeley. The Bone Lab, Professor Keaveny’s group within the Berkeley …

Sohn Research Laboratory

Our lab broadly focuses on two major themes: cancer and stem-cell biology. For cancer, we are developing and employing quantitative, label-free techniques to isolate, screen, and identify cells for biomedical-research and for clinical diagnostic and monitoring applications. For stem-cell biology, we are developing lab-on-a-chip systems that would enable us to study stem cells in their specialized …

Shadden Lab

Our research focuses on the advancement of theoretical and computational methods to quantify complex fluid flow. Much of our research is geared towards modeling and analyzing hemodynamic conditions in the cardiovascular system. This multidisciplinary research combines advances in medical imaging, mathematical modeling, and computational mechanics. Our motivations for this research are 3-fold: (1) to uncover …

Medical Polymer Group

The MPG represents an interdisciplinary team of graduate and undergraduate students who work closely with faculty, surgeons, and industry scientists in order to develop biomaterials for structural function in orthopedic applications. We bring together academic, industrial and clinical perspectives to improve designs and materials used in total joint reconstruction and related devices. Our research broadly …

Berkeley Robotics & Human Engineering Laboratory

Our research activities are focused on the design and control of a class of robotic systems worn or operated by humans to augment human mechanical strength, while the wearer’s intellect remains the central control system for manipulating the robot. Human power extenders can be used to maneuver heavy loads with great dexterity, speed, and precision, …

Molecular Cell Biomechanics Laboratory

Mofrad Lab combines the state-of-the-art molecular and multiscale biomechanics, computational biology and bioinformatics, and statistical machine learning approaches toward understanding and diagnosis of human diseases.

Berkeley Biomechanics Laboratory

Our lab is focused on soft tissue biomechanics and tissue regeneration. Specifically, our goal is to understand the mechanical function of the healthy, degenerated and injured soft tissues, including the intervertebral disc and articular cartilage, in order to develop more physiologically relevant repair strategies. Injury, through herniation, or degeneration may lead to debilitating lower back …

Tarek I. Zohdi

Tarek Zohdi

Will C. Hall Family Chair in Engineering

Associate Dean for Research, College of Engineering
Will C. Hall Endowed Chair
Chair of the UCB Computational & Data Science & Engineering Program
Professor of Mechanical Engineering

6117 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
zohdi@berkeley.edu

For more information see: Professor Zohdi's CV
Research Group Website
Books and Publications
Associate Dean for Research, COE
Editor CMAME
Editor-in-Chief, Comp. Particle Mechanics
Chair, D.E. in Comp. and Data Science Eng. Program
Faculty Scientist, Lawrence Berkeley National Lab
Director, UC-DEWA
Director, Fire Research Group
Director, Next Generation Food Systems Center
Academic Director, SCET

David Steigmann

David Steigmann

Professor of Mechanical Engineering

6133 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
dsteigmann@berkeley.edu
(510) 643-3165

For more information see: Current Classes Taught

To view Professor Steigmann’s CV, please click here.


Research Description:

Continuum, mechanics, shell theory, finite elasticity, variational methods, stability, surface stress, capillary phenomena, mechanics of thin films.

 

Key Publications:

To view a list of Professor Steigmann’s publications, please click here.

Lydia Sohn

Lydia Sohn

Almy C. Maynard and Agnes Offield Maynard Chair in Mechanical Engineering

Chancellor's Professor
Professor of Mechanical Engineering
Almy C. Maynard and Agnes Offield Maynard Chair in Mechanical Engineering

5118 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
sohn@berkeley.edu
(510) 642-5434

For more information see: Sohn Research Lab
Current Classes Taught

To view Professor Sohn’s CV, please click here.


Research Description:

Micro-nano engineering, bioengineering

 

Key Publications:

To view a list of Professor Sohn’s publications, please visit the Sohn Research Lab website.

Shawn Shadden

Shawn Shadden

Vice Chair of Graduate Studies
Professor of Mechanical Engineering

6149 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
shadden@berkeley.edu
(510) 664-9800

For more information see: Shadden Lab
Current Classes Taught

Research Description:

Cardiovascular Biomechanics, Computational Mechanics, Computational Fluid Dynamics, Dynamical Systems, Fluid Dynamics, Lagrangian Coherent Structures, Mathematical Modeling, Thrombosis

 

Key Publications:

To view a list of Professor Shadden’s publications, please visit the Shadden Lab website.

Ömer Savaş

Omer Savas

Professor of Mechanical Engineering

6113 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
savas@berkeley.edu
(510) 642-5705

For more information see: Current Classes Taught

To view Professor Savaş’ CV, please click here.


Research Description:

Fluid mechanics: aircraft wake vortices; biofluid mechanics; boundary layers; instrumentation; rotating flows; transient aerodynamics; turbulent flows; vortex dynamics

 

To learn more about Professor Savaş’ research, please click here.

 

Key Publications:

To view a list of Professor Savaş’ publications, please click here.

Lisa Pruitt

Lawrence Talbot Chair in Engineering

Professor of Mechanical Engineering
Lawrence Talbot Chair in Engineering

5134 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
lpruitt@berkeley.edu

For more information see: Medical Polymer Group
Current Classes Taught

To view Professor Pruitt’s CV, please click here.


Research Description:

Research is focused on structure-property relationships in orthopedic tissues, biomaterials and medical polymers. Current projects include the assessment of fatigue fracture mechanisms and tribological performance of orthopedic biomaterials, as well as characterization of orthopedic tissues and associated devices. Surface modifications using plasma chemistry are used to optimize polymers for medical applications. Attention is focused on wear, fatigue and multiaxial loading. Retrievals of orthopedic implants are characterized to model in vivo degradation and physiological loading. Biomechanical characterization of structural tissues is performed to assess clinical treatments and to develop constitutive relationships. Laboratory techniques for structural characterization include SEM, TEM, FEM, SAXS, USAXS, XPS, DSC, GPC, FTIR, AFM, confocal microscopy, wear testing, fatigue testing, fracture mechanics analysis, and nanoindentation. Research has been supported by NIH, NSF, ONR, DARPA, OREF and industry. Pedagogical experience includes curriculum development in mechanical engineering and bioengineering. Teaching includes freshman seminars; undergraduate courses on Mechanical Behavior and Processing of Materials, Structural Aspects of Biomaterials, and Principles of Bioengineering; graduate courses on Fracture Mechanics, Mechanical Behavior of Materials, and Polymer Engineering.

 

Key Publications:

2014

F. Ansari, C. Major, T. R. Norris, S. B. Gunther, M. Ries, and L. Pruitt. “Unscrewing instability of modular reverse shoulder prosthesis increases propensity for in vivo fracture: a report of two cases.” Journal of shoulder and elbow surgery/American Shoulder and Elbow Surgeons…[et al.] 23, no. 2 (2014): e40-5.

 

E.W. Patten, D. Van Citters, M. D. Ries, and L. Pruitt. “Quantifying cross-shear under translation, rolling, and rotation, and its effect on UHMWPE wear.” Wear 313, no. 1 (2014): 125-134.

 

To view a complete list of Professor Pruitt’s publications from previous years, please click here.

Panayiotis Papadopoulos

Byron and Elvira Nishkian Chair in Structural Engineering

Professor of Mechanical Engineering
Byron and Elvira Nishkian Chair in Structural Engineering

6131 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
panos@berkeley.edu
(510) 642-3358

For more information see: Computational Solid Mechanics Lab
Current Classes Taught

RELATED EXPERIENCE

7/1/04 – present : Professor, University of California, Berkeley
7/1/98 – 6/30/04 : Associate Professor, University of California, Berkeley
7/1/92 – 6/30/98 : Assistant Professor, University of California, Berkeley
1/1/92 – 6/30/92 : Post-Doctoral Researcher, University of California, Berkeley
8/1/91 – 12/31/91 : University Lecturer, University of California, Berkeley
1/1/88 – 8/31/91 : Graduate Research Assistant, University of California, Berkeley
8/1/87 – 5/31/90 : Graduate Student Instructor, University of California, Berkeley

 

UNIVERSITY DEGREES

Ph.D. Civil Engineering, University of California, Berkeley, December 1991
M.S. Civil Engineering, University of California, Berkeley, May 1987
Dipl. Civil Engineering, Aristotle University, Thessaloniki, Greece, July 1986


Research Description:

Computational mechanics, solid mechanics, biomechanics, applied mathematics

 

Key Publications:

To view a list of Professor Professor Papadopoulos’ publications, please visit the Computational Solid Mechanics Lab website.

Oliver M. O’Reilly

Distinguished Professor of Mechanical Engineering
Vice Provost for Undergraduate Education

5131 Etcheverry Hall/227 California Hall
University of California, Berkeley
Berkeley, CA 94720-1740
oreilly@berkeley.edu
(510) 642-0877

For more information see: Dynamics Lab
Current Classes Taught

Oliver M. O’Reilly is a professor in the Department of Mechanical Engineering and Interim Vice Provost for Undergraduate Education at the University of California at Berkeley. 

 

He received his B.E. in Mechanical Engineering from the National University of Ireland, Galway (NUIG). Subsequently, he received his M.S. and Ph.D. degrees in Theoretical and Applied Mechanics from Cornell University. At Cornell, he studied under Phil Holmes and Frank Moon. After spending two years as a postdoc at the Institut für Mechanik at ETH-Zürich under Jürg Dual, he joined the faculty in Mechanical Engineering at Cal in 1992. He has previously served as the Chair and Vice Chair of the Berkeley Division of the Academic Senate and as an Associate Dean for Graduate Education in the Division of Computing, Data Science, and Society.

 

His interests span the fields of continuum mechanics and nonlinear dynamics. He has a broad range of specializations including directed (or Cosserat) theories of deformable bodies, constrained rigid body dynamics, contact mechanics, linear and nonlinear vibrations and linear and nonlinear dynamics of deformable bodies. He has applied these interests to a range of applications including soft robots, MEMS resonators, brake squeal, the dynamics of toys, motorcycle navigation, axially moving media, artificial and natural satellites, spinal kinematics and vehicle collision dynamics. 

 

O’Reilly has coauthored over 100 archival journal articles, written three textbooks, coauthored a monograph, and is a co-inventor on two patents. He has also received multiple teaching awards including U.C. Berkeley’s Distinguished Teaching Award in 1999, the Pi-Tau-Sigma Professor of the Year Award in 2003 and the Tau-Beta-Pi Outstanding Faculty of the Year Award in 2013. He is also a recent recipient of the Berkeley Faculty Service Award. 

 

To view Professor O’Reilly’s CV, please click here.


Research Description:

Dynamics, Vibrations, Continuum Mechanics

 

Key Publications:

To view a list of Professor O’Reilly’s publications, please visit the Dynamics Lab website.

Grace O’Connell

Grace O'Connell

Associate Professor of Mechanical Engineering
Associate Dean for Inclusive Excellence, College of Engineering

5122 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
g.oconnell@berkeley.edu
(510) 642-3739

For more information see: O'Connell Lab
Current Classes Taught

Education
2001 – 2004 B.S. Aerospace Engineering, University of Maryland
2004 – 2009 Ph.D. Bioengineering, University of Pennsylvania
2009 – 2013 Postdoctoral Research Scientist, Columbia University


Research Description:

Biomechanics of cartilage and intervertebral disc; tissue engineering; continuum modeling of soft tissues; intervertebral disc function, degeneration, and regeneration

 

Key Publications:

2015

Tan AR, Alegre-Aguaron E, O’Connell GD, VandenBerg CD, Aaron RK, Vunjak-Novakovic G, Bulinski JC, Ateshian GA, Hung CT. Passage-Dependent Relationship between Mesenchymal Stem Cell Mobilization and Chondrogenic Potential. Osteoarthritis and Cartilage, In Press

 

2014

O’Connell GD, Newman IB, Carapezza MA. Effect of long-term osmotic loading culture on matrix synthesis from intervertebral disc cells. BioResearch, Oct 1;3(5):242-9, 2014.

 

Ponnurangam S, O’Connell GD, Chernyshova I, Woods K, Somasundaran P, Hung CT. Ceria nanoparticles modulate development and interleukin response of chondrocyte-seeded hydrogel constructs. Tissue Engineering, Part A, Nov; 20(21-22):2908-19, 2014.

 

O’Connell GD, Nims R, Green J, Cigan A, Ateshian GA, Hung CT. Time and dose-dependent effects of chondroitinase ABC on growth of engineered cartilage. eCells and Materials Journal, Vol. 27: 312-320, 2014.

 

To view a complete list of Professor O’Connell’s publications from previous years, please visit the Berkeley Biomechanics Laboratory website.

Mohammad R. K. Mofrad

Mohammad Mofrad

Professor of Mechanical Engineering and Bioengineering

208A Stanley Hall #1762
University of California, Berkeley
Berkeley, CA 94720-1762
mofrad@berkeley.edu
(510) 643-8165

For more information see: Molecular Cell Biomechanics Laboratory
Current Classes Taught

Education

1991  B.A.Sc., Sharif University of Technology

1994  M.A.Sc., University of Waterloo

1999  Ph.D., University of Toronto

 

Professional Experience

1999 – 2000  Post-Doc, Computer Science Department, University of Toronto

2000 – 2002  Post-Doc, MIT and Harvard Medical School/Mass. General Hospital

2002 – 2004  Principal Research Scientist, Biological and Mechanical Engineering, MIT

2005 – 2010  Assistant Professor, Department of Bioengineering, University of California, Berkeley

2010 – 2013  Associate Professor, Department of Bioengineering, University of California, Berkeley

2011               Visiting Professor, Department of Bioengineering, EPFL, Lausanne, Switzerland

2012 – 2013  Associate Professor, Department of Mechanical Engineering, University of California, Berkeley

2012 – Present  Faculty Scientist, Molecular Biophysics, Lawrence Berkeley National Lab

2012 – 2014  Faculty Director, UC Berkeley Master of Bioengineering (M.Eng) Program

2013 – Present  Professor, Departments of Bioengineering and Mechanical Engineering, University of California, Berkeley

2014 – 2015  Faculty Co-Director, Berkeley-UCSF Master of Translational Medicine (MTM) Program


Research Description:

Multiscale Biomechanics of Cardiovascular Disease and Brain Injury; Molecular and Cellular Mechanobiology; Mechanics of Integrin-Mediated Focal Adhesions; Mechanics of the Nuclear Pore and Nucleocytoplasmic Transport

 

Key Publications:

To view a list of Professor Mofrad’s publications, please visit the Molecular Cell Biomechanics Laboratory website and PubMed.

Liwei Lin

Lin

James Marshall Wells Academic Chair in Mechanical Engineering

Professor of Mechanical Engineering
James Marshall Wells Academic Chair
Co-Director, Berkeley Sensor & Actuator Center

5135 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
lwlin@berkeley.edu
(510) 643-5495

For more information see: Lin Lab
Lin Home Page
Current Classes Taught

2006 – 2009  Vice Chair – Graduate Study, Mechanical Engineering Department, University of California at Berkeley

2004  Professor, Mechanical Engineering Department, University of California at Berkeley

2001  Associate Professor, Mechanical Engineering Department, University of California at Berkeley

1999  Assistant Professor, Mechanical Engineering Department, University of California at Berkeley

1996  Assistant Professor, Mechanical Engineering Department, University of Michigan

1994  Associate Professor, Institute of Applied Mechanics, National Taiwan University

1993  Senior Research Scientist, BEI Electronics Inc.

1993  PhD, Mechanical Engineering, University of California at Berkeley

1991  MS, Mechanical Engineering, University of California at Berkeley

1986  BS, Power Mechanical Engineering, National Tsing Hua University


Research Description:

MEMS (Microelectromechanical Systems); NEMS (Nanoelectromechanical Systems); Nanotechnology; design and manufacturing of microsensors and microactuators; development of micromachining processes by silicon surface/bulk micromachining; micromolding process; mechanical issues in MEMS including heat transfer, solid/fluid mechanics, and dynamics.

 

Key Publications:

For a list of Professor Lin’s publications, please click here.

Dorian Liepmann

Liepmann

Professor of Mechanical Engineering and BioEngineering

280 Hearst Memorial Mining Building
University of California at Berkeley
Berkeley, CA 94720-1762
liepmann@berkeley.edu
(510) 355-8353

For more information see: Liepmann Lab
Current Classes Taught

Research Description:

BioMEMS, microfluid dynamics, experimental biofluid dynamics, hemodynamics associated with valvular heart disease and other cardiac and arterial flows.

 

Key Publications:

2015

  • Paredes, J., Fink, K.D., Novak, R. and Liepmann, D. (2015) “Self-anchoring nickel microelectrodes for rapid fabrication of functional thermoplastic microfluidic prototypes.” Sensors and Actuators B: Chemical, 216:263-270.
  • Aran, K., Paredes, J., Rafi, M., Yau, J., Acharya, A., Zibinsky, M., Liepmann, D., and Murthy, N. (2015) “Stimuli-Responsive Electrodes Detect Oxidative Stress and Liver Injury.” Advanced Materials, 27(8), 1432.
  • Viswanathan, S., Narayanan, T.N., Aran, K., Fink, K.D., Paredes, J., Ajayan, P.M., Filipek, S., Miszta, P., Tekin, H.C., Inci, F., Demirci, U., Li, P., Bolotin, K.I., Liepmann, D. and Renugopalakrishanan, V. (2015) “Grephene-protein field effect biosensors: glucose sensing.” Materials Today, http://dx.doi.org/10.1016/j.mattod.2015.04.003

 

2014

  • Aran, K., Paredes, J., Yau, J., Srinivasan, S., Murthy, N. and Liepmann, D.  (2014) “An Enzyme-Free Digital Biosensor for Detection of Reactive Oxygen Species.” The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX. October 26-30, 2014
  • Paredes, J., Chooljian, M., Fink, K.D., and Liepmann, D. “Rapid fabrication method for plastic microfluidic devices with embedded 2D and 3D microelectrodes and its application to electroporation and cell lysis on chip.” The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX. October 26-30, 2014
  • Aran, K., Paredes, J., Acharya, A., Yau, J., Liepmann, D. and N. Murthy. “A Novel ROS Responsive Polymer Based Lab-on-a-Chip Sensor for Detection of Circulating Lipid Hydroperoxides” BMES, San Antonio, TX, October 22-25, 2014.
  • Paredes, J., Fink, K.D., Chooljian, M., and D. Liepmann. “Integrating 2D and 3D Microelectrodes in Plastic Microfluidic Devices Allowing Spatial and Temporal  Control of Electric Fields for Detection or Stimulation.” BMES, San Antonio, TX, October 22-25, 2014.
  • Aran, K., Paredes, J., Lee, K., Acharya, A., Liepmann, D. and N. Murthy. “A Battery-less Pressure Driven Smart Pill for Oral to Systemic Protein Delivery.” BMES, San Antonio, TX, October 22-25, 2014.
  • Fink, K., Paredes, J. and Liepmann, D. (2013) The Role of Erythrocyte Size and Shape in Microchannel Fluid Dynamics. American Physical Society Division of Fluid Dynamics Annual Meeting, Pittsburgh, PA.
  • Kim, T. N., Goodwill, P. W., Chen, Y., Conolly, S. M., Schaffer, C. B., Liepmann, D., & Wang, R. A. (2012). Line-scanning particle image velocimetry: an optical approach for quantifying a wide range of blood flow speeds in live animals. PloS one, 7(6), e38590.
  • Gharib, M., Azizgolshani, H., Gharib, M., & Liepmann, D. (2011). Combined Electro-chemical Stimulation to Reduce the Required Current for Muscle Contraction. FASEB Journal, 25, 1051-39.
  • Gulati, S., Dutcher, C. S., Liepmann, D., & Muller, S. J. (2010). Elastic secondary flows in sharp 90 degree micro-bends: A comparison of PEO and DNA solutions. Journal of Rheology (1978-present), 54(2), 375-392.
  • Thakar, R.G., Cheng, Q., Patel, S., Chu, J., Nasir, M., Liepmann, D., Komvopoulos, K. and Li, S. (2009) Cell-Shape Regulation of Smooth Muscle Cell Proliferation. Biophysical Journal 96(8):3423-3432.
  • Häfeli, U. O., Mokhtari, A., Liepmann, D., & Stoeber, B. (2009). In vivo evaluation of a microneedle-based miniature syringe for intradermal drug delivery. Biomedical microdevices, 11(5), 943-950.
  • Gulati, S., Muller, S. J., & Liepmann, D. (2008). Direct measurements of viscoelastic flows of DNA in a 2: 1 abrupt planar micro-contraction. Journal of Non-Newtonian Fluid Mechanics, 155(1), 51-66.
  • Liepmann, D., Pisano, A., Stoeber, B., & Zimmermann, S. (2008). U.S. Patent No. 7,415,299. Washington, DC: U.S. Patent and Trademark Office
  • Gulati, S., Liepmann, D., & Muller, S. J. (2008). Elastic secondary flows of semidilute DNA solutions in abrupt 90° microbends. Physical Review E, 78(3), 036314.

 

To view a list of Professor Liepmann’s publications from previous years, please visit the Liepmann Lab website.

Kyriakos Komvopoulos

Komvopoulos-Kyriakos

Distinguished Professor of Mechanical Engineering

5143 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
kyriakos@me.berkeley.edu
(510) 642-2563

For more information see: Current Classes Taught

Professor Komvopoulos has been in the faculty of the Department of Mechanical Engineering at the University of California, Berkeley (UCB) since 1989. Before joining UCB, he was in the faculty of the Department of Mechanical and Industrial Engineering at the University of Illinois at Urbana-Champaign (1986-1989). Professor Komvopoulos is internationally known for pioneering research in surface nanosciences and nanoengineering, with important implications in several emerging technologies including communications, microelectronics, information storage, and biotechnology. He is the founder and director of the Surface Sciences and Engineering Laboratory (SSEL) and the Computational Surface Mechanics Laboratory (CSML) and holds the positions of Professor of Mechanical Engineering at UCB, Faculty Scientist, Materials Sciences Division, Lawrence Berkeley National Laboratory (LBNL), Principal Investigator, The Berkeley Stem Cell Center, and Principal Investigator, Center for Information Technology in the Interest of Society (CITRIS).

 

The research of Professor Komvopoulos is at the interfaces of mechanical and electrical engineering, materials sciences, surface physical chemistry, bioengineering, and biology. His work is characterized by a multidisciplinary nature and the combination of analytical and experimental techniques used to analyze complex surface and interface phenomena. His research is based on the integration of fundamentals from mechanics, materials, surface chemistry, and biology, and spans a broad range of scales, from the mesoscopic to the atomic and molecular levels. 

 

Early research accomplishments of Professor Komvopoulos include contact deformation at submicron scales, new friction theories of surfaces interacting in the presence of physicochemically adsorbed monolayers, surface plasticity and fracture of contacting bodies, acoustic emission in surface sliding and machining, synthesis and characterization of ultrathin diamondlike and amorphous carbon films, adhesion forces in miniaturized electromechanical systems, and rheological behavior of boundary films. 

 

In the past two decades, Professor Komvopoulos broadened his research activities, branching into the exploration of various surface microprobe techniques for atomic and molecular level surface analysis, synthesis of self-assembled organic monolayers for reducing adhesion between silicon microdevices, invention of plasma-assisted surface treatments for biopolymers (used in total joint replacements, catheters for minimally invasive treatment of diseased arteries, and cell platforms), deposition of ultrathin (a few atomic layers) amorphous carbon films by sputtering and filtered cathodic vacuum arc for ultrahigh-density magnetic recording and heat-assisted magnetic recording, phase transformations and nanomechanical properties of shape-memory alloys (both in thin-film and bulk form) for retina disks and artery stents, a surface-specific spectroscopy technique (infrared-visible sum frequency generation (SFG) vibrational spectroscopy) for in-situ studies of entropically driven molecular rearrangement at various biopolymer surfaces due to in-plane and out-of-plane stretching and aging effects.

 

Professor Komvopoulos’ most recent work includes plasma-assisted polymer surface functionalization for controlling adhesion and growth of cells, protein secretion due to mechanotransduction in articular cartilage, cell mechanics, patterned media for single-cell growth, and cell infiltration into fibrous scaffolds synthesized by electrospinning, new electrode materials for lithium-ion batteries, flexible and stretchable bioelectronics, skin mechanics, and transdermal drug delivery by microneedle arrays, mechanics of biological surfaces, and synthesis of scaffolds with special cues for enhanced biofunctionality.

 

Professor Komvopoulos’ research is documented in 379 publications consisting of 277 papers published in peer-reviewed archival journals, 71 papers in refereed conference proceedings, 19 papers in symposium proceedings, 2 book chapters, 65 technical reports, and 10 US patents. As of June 2021, Professor Komvopoulos’ publications and patents have been cited more than 13,750 times (h-index = 62, Google Scholar). He has also authored an undergraduate-level textbook (Mechanical Testing of Engineering Materials) and co-authored two monographs (1999 Interface Tribology Towards 100 Gbit/in2; Long Term Durability of Structural Materials: Durability 2000). He has given 225 scholarly presentations at various international conferences, academic institutions, national laboratories, industries, and various media, supervised the research and dissertations of 58 graduate students (33 PhD and 25 MS) and 17 post-doctoral students, visiting faculty, and industry fellows, and consulted with a wide range of industries and law firms on various litigation matters. 

 

Professor Komvopoulos has been elected to the grade of Fellow of STLE (2004) and ASME (2000) and has been the recipient of several awards, including NSF Presidential Young Investigator Award (1989-1996), IBM Faculty Development Award (1990-1992), Berkeley Engineering Fund Award (1989-1990), ASME B. L. Newkirk Award (1988), and NSF Engineering Initiation Award (1987).

 

At UCB, Professor Komvopoulos teaches undergraduate and graduate courses on Mechanical Behavior of Materials, Plasticity, Fracture, Fatigue, and Tribology and devotes significant time to administration duties at the Department, College, and University system-wide levels. His most recent system-wide committee service includes UC Faculty Welfare, Assembly Representative, Divisional Council, Educational Technology, Courses of Instruction, Graduate Study, and Committee on Academic Planning and Resource Allocation.


Research Description:

Theoretical and numerical studies in nano-/micro-scale contact mechanics, tribology, mechanical behavior of bulk and thin-film materials, deposition and characterization of single and multi-layer ultrathin films by sputtering and filtered cathodic vacuum arc methods, reliability of micro-electro-mechanical systems (MEMS), surface force microprobe techniques, surface modification of biopolymers, surface chemical functionalization for enhanced biocompatibility and cell activity, mechanotransduction effects at the single-cell and tissue levels, scaffolds for tissue engineering, and flexible/stretchable bioelectronics.

 

To learn more about Professor Komvopoulos’ research, please click here.

 

To view a list of Professor Komvopoulos’ supervised current and past graduate students and visiting scholars, please click here.

 

Key Publications:

To view a list of Professor Komvopoulos’ publications, please click here.

Tony M. Keaveny

Keaveny-Tony

Professor of Mechanical Engineering and Bioengineering

5124 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
tonykeaveny@berkeley.edu
(510) 390-1626

For more information see: Bone Biomechanics Lab
Current Classes Taught

Tony Keaveny is a Professor in the Departments of Mechanical Engineering and Bioengineering at the University of California at Berkeley, and the director of the Berkeley Orthopaedic Biomechanics Laboratory. Dr. Keaveny received his B.E. (1984) degree in Mechanical Engineering from University College Dublin, Ireland, and his M.S. (1988) and Ph.D. (1991) degrees, also in Mechanical Engineering, from Cornell University. He spent one year (1990-1991) as a Maurice Mueller Post-Doctoral Fellow in Orthopaedic Biomechanics in the Orthopaedic Biomechanics Laboratory at Beth Israel Hospital, Boston, after which he joined the permanent staff there as a Senior Research Associate (1991- 1993). At the same time, Dr. Keaveny was appointed an Instructor of Orthopaedic Surgery at Harvard Medical School and joined the faculty of the Harvard/M.I.T. Health Sciences and Technology Program. He left Boston and joined the Berkeley faculty in 1993, at which time he established the Berkeley Orthopaedic Biomechanics Laboratory.

 

Dr. Keaveny has served as Principal Investigator on an NIH FIRST Award and several NIH R01 and R21 grants, a Whitaker Biomedical Engineering Research Grant, an NSF CAREER Award, and numerous industrial grants. In 1996, he received the YC Fung Young Investigator Award from the Bioengineering Division of the American Society of Mechanical Engineers. He was the 2010 winner of the Van C. Mow Medal. As director of the Berkeley OBL, Dr. Keaveny directs and supervises all research in the laboratory, and acts as the faculty research mentor for all students.


Research Description:

Biomechanics: mechanical behavior of bone, finite element modeling and experimentation, design of bone-implant systems, tissue engineering

 

Key Publications:

To view a list of Professor Keaveny’s publications, please click here.

Homayoon Kazerooni

Kazerooni-Homayoon

Professor of Mechanical Engineering

6147 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
kazerooni@berkeley.edu
(510) 642-2964

For more information see: Berkeley Robotics & Human Engineering Laboratory
Current Classes Taught

Dr. Kazerooni is a professor of Mechanical Engineering at the University of California, Berkeley, where he also serves as the director of the Berkeley Robotics and Human Engineering Laboratory. With more than 30 years of mechanical engineering experience and a doctorate degree from MIT, he is a leading expert in robotics, control sciences, exoskeletons, medical devices, human-machine systems and augmentation, bioengineering, mechatronics design, and intelligent assist devices.  Prior to his more well-known research on lower extremity exoskeletons, Dr. Kazerooni led his team at Berkeley to successfully develop robotics systems that enhanced human upper extremity strength.  The results of this work led to a new class of Intelligent Assist Devices (IAD) that are currently marketed worldwide by leading material handling corporations for use by manual laborers in distribution centers and factories globally.  

 

Dr. Kazerooni’s later work focuses on the control of human-machine systems specific to lower human extremities. After developing BLEEX, ExoHiker, and ExoClimber–three load-carrying exoskeletons–his team at Berkeley created HULC (Human Universal Load Carrier). It is the first energetically-autonomous, orthotic, lower extremity exoskeleton that allows its user to carry 200-pound weights in various terrains for an extended period, without becoming physically overwhelmed.  The technology was licensed to Lockheed Martin. Dr. Kazerooni has also developed lower-extremity technology to aid persons who have experienced a stroke, spinal cord injuries, or health conditions that obligate them to use a wheelchair.  His medical exoskeletons, Ekso and Phoenix have successfully allowed those who have been paralyzed to walk, stand, and speak face to face with peers in an upright position. The technologies related to Ekso and Phoenix are licensed to Ekso Bionics and suitX. 

 

In addition to his teaching work and research experience in academia, Dr. Kazerooni is also an entrepreneur. In 2005, he founded Ekso Bionics (eksobionics.com), which went on to become a publicly-owned company in 2014 and now supplies medical exoskeleton (Ekso) to a great number of rehabilitation centers worldwide.  Later he founded suitX (suitx.com), a VC, industry, and government funded company that provides industrial and medical exoskeletons.  suitX was acquired by Ottobock, the largest European medical device company in late 2021.

 

Dr. Kazerooni has won numerous awards including Discover Magazine’s Technological Innovation Award, the McKnight-Land Grant Professorship, and has been a recipient of the outstanding ASME Investigator Award. His research was recognized as the most innovative technology of the year in New York Times Magazine. He has served in a variety of leadership roles in the mechanical engineering community and was notably the editor of two journals: ASME Journal of Dynamics Systems and Control and IEEE Transaction on Mechatronics. A recognized authority on robotics, Dr. Kazerooni has published more than 200 articles to date, delivered over 130 plenary lectures internationally, and is the inventors of over 200 patents.


Research Description:

Bioengineering, robotics, control systems, mechatronics, design, automated manufacturing and human-machine systems

 

Key Publications:

To view a list of Professor Kazerooni’s publications, please visit the Berkeley Robotics & Human Engineering Laboratory’s website.

Costas Grigoropoulos

Grigoropoulos-Costas

A. Martin Berlin Chair in Mechanical Engineering

A. Martin Berlin Chair in Mechanical Engineering
Distinguished Professor of Mechanical Engineering

6129 Etcheverry Hall
University of California, Berkeley
Berkeley, CA 94720-1740
cgrigoro@berkeley.edu
(510) 642-2525

For more information see: Laser Thermal Lab
Current Classes Taught

Costas P. Grigoropoulos received his Diploma Degrees in Naval Architecture and Marine Engineering (1978), and in Mechanical Engineering (1980) from the National Technical University of Athens, Greece. He holds a M.Sc. degree (1983), and a Ph.D. (1986), both in Mechanical Engineering from Columbia University. He joined the faculty of the Department of Mechanical Engineering at the University of California at Berkeley as an Assistant Professor in 1990, after serving as an Assistant Professor of Mechanical Engineering at the University of Washington from 1986-1990. He was promoted to Associate Professor in July 1993 and to Professor in Mechanical Engineering in July 1997. He has conducted research at the Xerox Mechanical Engineering Sciences Laboratory, the IBM Almaden Research Center and the Institute of Electronic Structure and Laser, FORTH, Greece. He is Faculty Staff Scientist with the Environmental Energy Technologies Division of the Lawrence Berkeley National Laboratory.


Research Description:

Laser materials processing and micro/nano-machining, fabrication of flexible electronics and energy conversion devices, characterization of micro/nanofluidic transport, laser interactions with biological materials, architected materials.

 

Key Publications:

To view a list of Professor Grigoropoulos’ publications, please visit the Laser Thermal Lab website.

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